Chemokines act as ligands for the chemokine

2019-08-20

Chemokines act as ligands for the chemokine receptors, which possess 7-transmembran domain-type proteins functionally coupled to G proteins. Leukocytes express 19 chemokine receptors which control their influx and activation at the site of inflammation.

CDKs as Direct Coactivators of Proinflammatory

2019-08-19

CDKs as Direct Coactivators of Proinflammatory Transcription Factors CDKs fuel inflammation by triggering the function of proinflammatory transcription factors such as NF-κB, STAT3, and AP-1.

Conclusion Rational design of highly selective

2019-08-17

Conclusion Rational design of highly selective fluorescent probes to detect G-quadruplexes is of profound importance for basic research. On this basis, we designed and synthesized a series of N-alkylated styrylquinolinium dyes Ls-1, Ls-2 and Ls-3.

Introduction Protein ubiquitination

2019-08-16

Introduction Protein ubiquitination is a posttranslational modification that plays a major role in almost all cellular processes in eukaryotes (Hochstrasser, 2009; Komander & Rape, 2012).

Our study found a significant association

2019-08-15

Our study found a significant association between the degree of primary tumor lobulation and EGFR mutations status (P < 0.001).

Discussion Although DNA has a limited chemical

2019-08-14

Discussion Although DNA has a limited chemical stability it has long been known that DNA in blood stains may remain relative stable for weeks, months, or even years at ambient temperature,1, 2, 3, 4, 5, 6 and samples (e.g., reference samples) that have been transferred to a matrix, e.g., FTA® paper, containing stabilizing agents are stable for at least 4 years.

The HEV vaccine developed based

2019-08-13

The HEV vaccine, developed based on p239 particles, is of good efficacy, immunogenicity and safety, and was licensed in China in 2012.

Hello world!

2018-07-29