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The fibrillogenesis process of collagen is understood to
2020-01-20
The fibrillogenesis process of collagen is understood to initiate in the extracellular space near the plasma membrane where secretory vesicles form regions of deep invagination. However, it is not clear how and when collagen-binding proteins interact with collagen molecules during fibrillogenesis or
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Behaviors were compared between saline and amphetamine
2020-01-20
Behaviors were compared between saline and amphetamine pre-treatment groups at 24h and 2 weeks following the last treatment, or between pre-treatment groups that received vehicle or ASV-30 infusions, using separate two-way ANOVAs. Significant effects were analyzed further using Student–Newman–Keuls
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br Conclusion br Introduction The morphological variability
2020-01-20
Conclusion Introduction The morphological variability of aquatic plants is well documented, and in some cases has seriously constrained taxonomic resolution (Sculthorpe, 1967, Santamaría, 2002). Many of these variations are caused by the extensive phenotypic plasticity of aquatic plants, but t
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br Cholesterol handling in the
2020-01-20
Cholesterol handling in the arterial wall cells Foam cell formation in the arterial intima is a major hallmark of early-stage atherosclerotic lesions, which is attributed to uncontrolled uptake of modified lipoproteins, excess cholesterol esterification and impaired cholesterol release [44]. As a
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Just as Dorin et al and Nguyen
2020-01-20
Just as Dorin et al. [2] and Nguyen et al. [3] write in regard to their models, our static model can be used to estimate the affinities of Carbetocin receptor to albumin and CBG. Dorin et al. [2] estimates the K, but not K, since they find that their model is not particular sensitive towards change
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In our opinion the precise function of
2020-01-19
In our opinion, the precise function of AE of S. mansoni (Sm32) remains unclear, and accurate knowledge of the three dimensional structure of this enzyme would be valuable for a better understanding the molecular basis of many of its properties, including its role in the host-parasite interaction, a
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Industrial fermentation aims to produce valuable
2020-01-19
Industrial fermentation aims to produce valuable products from cheap feedstocks by utilizing diverse microbial functions through aerobic or anaerobic fermentation [[8], [9], [10]]. During anaerobic fermentation, the reducing power is mostly directed to product synthesis rather than being oxidized, r
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Previously published results on this topic
2020-01-19
Previously published results on this topic are inconsistent. Stressin1-A, a novel CRF1 receptor agonist, increased anxiety-like behavior in the social interaction and shock-probe tests [51]. Pharmacological blockade of CRF1 (NBI-30775) reversed both CRF-induced increases in startle and CRF-induced d
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Sterol regulatory element binding proteins SREBPs regulate t
2020-01-19
Sterol regulatory element binding proteins (SREBPs) regulate transcription of genes involved in fatty Levonorgestrel synthesis [38] (fatty acid synthase, and acetyl-CoA carboxylase) as well as triglyceride synthesis [39]. SREBP-1 protein levels are reduced in 3T3-F442A adipocytes [40] and increased
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Leukotrienes themselves are implicated in the development of
2020-01-19
Leukotrienes themselves are implicated in the development of gastrointestinal ulcers, asthmas, and different inflammatory processes [18], [19]. It is noteworthy that COX isozymes and LOX share the same substrate arachidonic acid; therefore, inhibition of prostaglandins production by cyclooxygenase p
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Secondary and primary studies have considered the decision t
2020-01-19
Secondary and primary studies have considered the decision to select the provider and to select components after the component origin is chosen. Examples of secondary and primary studies outside our scope, but still related to decision-making are listed in Tables 1 and 2. The secondary and primary s
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In conclusion the results obtained in
2020-01-19
In conclusion, the results obtained in this study and those recently reported by our group (Abdel-Samad et al., 2012) clearly indicate that a dialogue indeed exists between the systems of NPY and ET-1 at the level of human endocardial endothelial cells, since these cells, whether isolated from the r
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The most common pathology associated with FGR is poor
2020-01-19
The most common pathology associated with FGR is poor placental perfusion as a result of abnormal placentation [4]. Placental developmental disorders and insufficient hormone synthesis may lead to FGR [5,6]. However, the exact mechanism responsible for abnormal placental development remains unclear.
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Pursuant to our in vitro data that neutrophilic
2020-01-19
Pursuant to our in vitro data that neutrophilic elastase activated the elastase-dependent oncolytic virus, we initially hypothesized that tumor-infiltrating neutrophils could be the source for elastase in tumor tissue. However, we did not detect neutrophils in the PANC-1 tumor tissue where we observ
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Fluticasone propionate Another interesting finding regarding
2020-01-17
Another interesting finding regarding substrate selectivity of iPLA2-VIA in whole cellular systems stems from the observation that some of the major species hydrolyzed by the enzyme contain a 16:1 fatty Fluticasone propionate at the sn-2 position [57,119], raising the possibility that iPLA2-VIA may
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