• Natural compounds present in medicinal and or nutritional pl

  2025-01-31

  

  Natural compounds, present in medicinal and/or nutritional plants as well as in macrofungi sources, have stimulated a great interest from the pharmaceutical industry. Different natural compounds such as phenolic compounds, alkaloids, terpenoids among others, have shown strong antiangiogenic effects

• MT SGL encourages a individual feature selection based on

  2025-01-31

  

  MT-SGL encourages (a) individual feature selection based on the utility of the features across all tasks with ℓ2,1-norm and (b) task specific group selection based on the utility of the group with G2,1-norm, i.e., 94 8 regions of interest (ROI) for that task. Unlike basic SGL for regression (Chatte

• br Experimental section br Introduction Microglia were

  2025-01-31

  

  Experimental section Introduction Microglia were discovered as a novel cell population in ER 50891 synthesis in 1933 by a Spanish physician and histologist Pío del Río-Hortega [1]. In the eye, scientists used Hortega's staining technique to label the microglia in the retinal outer plexiform l

• PF-573228 The consensus amino acid recognition sequence

  2025-01-27

  

  The consensus amino PF-573228 recognition sequence for p38α substrates is (Ser/Thr)Pro (Cuadrado and Nebreda, 2010), typically assisted by upstream docking motifs (Remenyi et al, 2005, Sharrocks et al, 2000). P450c17 has 32 Ser and 25 Thr residues, of which only Thr 341 and Ser 427 are immediately

• The skin permeability barrier is important for the preventio

  2025-01-27

  

  The skin permeability barrier is important for the prevention of loss of water and electrolytes from inside the body and for protection against the invasion of external pathogens, allergens, and harmful compounds. Multi-layered lipids, called lipid lamellae, are present in the outermost cell layer o

• Transient transfection with ATR kinase dead D

  2025-01-27

  

  Transient transfection with ATR kinase-dead (D2475→A) [30] and ATM kinase-dead (D2870→Ala and N2875→K) [31] constructs was performed using Fugene 6 (Roche Applied Science, Indianapolis). Three microliters of fugene 6+1μg plasmid was used in transfections using 6-well plates at 2×105 cells/well and

• Estrogen exerts its genomic action via estrogen nuclear

  2025-01-27

  

  Estrogen exerts its genomic action via glut1 nuclear receptor: ERα and ERβ. The distribution of ERα and/or ERβ positive neurons in CNS of different species has been mapped extensively by various methods [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], although there are some differences

• Although apelin g kg shows

  2025-01-27

  

  Although apelin 60μg/kg shows negative (early) and positive (late) inotropic effects, since ERK1/2 phosphorylation starts at the min 5 of administration [6], ERK1/2 phosphorylation mediate positive inotropic effects of apelin 60μg/kg. After the simultaneous inhibition of KOR and APJ the phosphoryla

• br Materials and methods br Results br Discussion

  2025-01-27

  

  Materials and methods Results Discussion In this study, the orphan receptor GPR25 was cloned from several representative vertebrate species including zebrafish. Although the overall amino 78416 sequence identity among these species is not high (38–52%), our synteny analysis clearly indicat

• Furthermore because most of foods

  2025-01-27

  

  Furthermore, because most of foods and beverages have been consumed after processing, researchers have focused on the effects of processing (e.g. blanching, cooking, drying, cooling, freezing, high-pressure treatment, pulsed electric field) on total antioxidant capacity of foods. In general, there w

• br Material and methods br Results Table shows that in

  2025-01-27

  

  Material and methods Results Table 1 shows that in addition to Leu/CysAP and DPPIV, genes for AspAP, ArgAP, MetAP, APM and PSA are expressed in adipocytes. The kinetic parameters of these AP are also shown in Table 1, revealing that APM has the highest Vmax and catalytic efficiency (Kcat/Km),

• br Introduction The structural similarities between

  2025-01-27

  

  Introduction The structural similarities between puromycin (1, Fig. 1) and the aminoacyl adenyl terminal of aminoacyl–tRNA allow it to terminate the protein synthesis process by causing premature release of a polypeptide from the ribosome [1], [2]. Tremendous progress in the study of puromycin an

• Sperm total motility and hyperactivated motility are mediate

  2025-01-26

  

  Sperm total motility and hyperactivated motility are mediated by PLD-dependent Serotonin 1B receptor blocker polymerization [20]. Reduction of PIP2 synthesis inhibited actin polymerization and motility, and increasing PIP2 synthesis enhanced these activities. Furthermore, sperm demonstrating low mo

• Introduction Microdialysis is an in

  2025-01-26

  

  Introduction Microdialysis is an in vivo-technique which allows continuous sampling of small molecular weight substances (such as neurotransmitters, metabolites and neuropeptides) from the extracellular space of different tissues or organs, e.g. brain, muscle or skin. While the implantation of the

• Although effects of low concentrations of agonist were not a

  2025-01-26

  

  Although effects of low concentrations of agonist were not as thoroughly documented for heteromeric receptors such as the major Multiplex Immunofluorescence Kit α4β2 nAChR, a similar mechanism of action was described to explain the potentiation of these receptors with low concentrations of acetylch

14092 records 18/940 page Previous Next First page 上5页 1617181920 下5页 Last page